Those 3 words are the New Madrid Fault. In 1811 an earthquake of major magnitude hit Southern Illinois , a quake so powerful it literally changed the course of the Mississippi River and allegedly ran church bells in Boston. So yes a serious natural disaster could hit here and cripple us to the degree we are witnessing in North Carolina and elsewhere so this article resonates.
Yikes
https://www.dailymail.com/sciencetech/article-15976897/giant-jellyfish-invade-new-england-beaches.html

